Unknown,Transcriptomics,Genomics,Proteomics

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Quantitative Genomics study of sex dimorphism in D. Melanogaster


ABSTRACT: A diallel including reciprocals but not selfs experiment. Keywords: Agilent microarray, sexual dimorphism, genetical genomics, genetic variation Nine randomly selected D. melanogaster lines were used as parents for this diallel. Male and female intact adult progeny were collected. Crosses were repeated in four independent sub blocks such that every cross appeared with every other cross at least once. Two sub blocks were pooled for each replicate. Each array was a pair of male and females from the same cross with the dye flipped between replicates

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Lauren McIntyre 

PROVIDER: E-GEOD-5181 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Simpler mode of inheritance of transcriptional variation in male Drosophila melanogaster.

Wayne Marta L ML   Telonis-Scott Marina M   Bono Lisa M LM   Harshman Larry L   Kopp Artyom A   Nuzhdin Sergey V SV   McIntyre Lauren M LM  

Proceedings of the National Academy of Sciences of the United States of America 20071114 47


Sexual selection drives faster evolution in males. The X chromosome is potentially an important target for sexual selection, because hemizygosity in males permits accumulation of alleles, causing tradeoffs in fitness between sexes. Hemizygosity of the X could cause fundamentally different modes of inheritance between the sexes, with more additive variation in males and more nonadditive variation in females. Indeed, we find that genetic variation for the transcriptome is primarily additive in mal  ...[more]

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