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A species-specific nucleosomal signature defines a periodic distribution of amino acids in proteins

ABSTRACT: Sequencing of mononucleosomal DNA during asynchronous mitosis in Schizosaccharomyces pombe, Schizosaccharomyces octosporus, Schizosaccharomyces japonicus and Saccharomyces cerevisiae Samples from mononucleosomal DNA from asynchronous mitosis of four species of budding (Saccharomyces cerevisiae W303-1a) and fission yeasts (S. pombe wild type 972h-, S. octosporus CBS1804, S. japonicus var. japonicus ade12- FY53) were sequenced (Illumina Genome Analyzer IIx and HiSeq 2500) using the single read and paired end protocol.

ORGANISM(S): Schizosaccharomyces octosporus

SUBMITTER: Luis Quintales

PROVIDER: E-GEOD-52170 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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A species-specific nucleosomal signature defines a periodic distribution of amino acids in proteins.

Quintales Luis L Soriano Ignacio I Vázquez Enrique E Segurado Mónica M Antequera Francisco F

Open biology 20150401 4

Nucleosomes are the basic structural units of chromatin. Most of the yeast genome is organized in a pattern of positioned nucleosomes that is stably maintained under a wide range of physiological conditions. In this work, we have searched for sequence determinants associated with positioned nucleosomes in four species of fission and budding yeasts. We show that mononucleosomal DNA follows a highly structured base composition pattern, which differs among species despite the high degree of histone ...[more]

PMID: 25854683

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