Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Kevin Lebrigand
PROVIDER: E-GEOD-52299 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Carcinogenesis 20131228 5
Incidence of cutaneous squamous cell carcinomas (cSCCs) constantly increases in the Caucasian population. Developing preferentially on precancerous lesions such as actinic keratoses due to chronic sunlight exposure, cSCCs result from the malignant transformation of keratinocytes. Although a resection of the primary tumor is usually curative, a subset of aggressive cSCCs shows a high risk of recurrence and metastases. The characterization of the molecular dysfunctions involved in cSCC development ...[more]