Unknown,Transcriptomics,Genomics,Proteomics

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Microarray analysis of gene expression profiles in PBHA-treated THP-1 cells after LPS stimulation


ABSTRACT: Using microarray analysis, 219 differentially expressed genes were isolated between the LPS group and LPS/PBHA treatment-group (fold change > or < 1.5). These genes were analyzed by KEGG system to reveal the important issues. The analyses of gene ontology were shown that the genes of the specific classes M-bM-^@M-^\Chemokine signaling pathwayM-bM-^@M-^], M-bM-^@M-^]Cytokine-cytokine receptor interactionM-bM-^@M-^], M-bM-^@M-^]RIG-I-like receptor signaling pathwayM-bM-^@M-^], M-bM-^@M-^]Leukocyte transendothelial migrationM-bM-^@M-^], and M-bM-^@M-^\MAPK signaling pathwayM-bM-^@M-^] showed markedly different patterns between both groups by KEGG analysis system. In this study presented here, human THP-1 cells were pretreated with only vehicle (resting group), vehicle and LPS (50 ng/ml), or PBHA (10 M-NM-

ORGANISM(S): Homo sapiens

SUBMITTER: George Hsiao 

PROVIDER: E-GEOD-52365 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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