MG-treated vs non-treated ST2 cells Mouse 32K
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Sohei Kitazawa
PROVIDER: E-GEOD-52475 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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Project description:In diabetics, methylglyoxal (MG), a glucose-derived metabolite, plays a noxious role by inducing oxidative stress, which causes and exacerbates a series of complications. With the use of microarray analysis, we comprehensively screened the gene expression profiles of ST2 cells, derived from a multipotent bone marrow stromal cell line, in the presence or absence of oxidative stress induced by100 μM methylglyoxal (MG) treatment to charactrize genes related to diabetic complications.
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