Unknown,Transcriptomics,Genomics,Proteomics

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Transcriptomics of the Fetal Hypothalamic Response to Brachiocephalic Occusion and Estradiol Treatment


ABSTRACT: Estradiol (E2) is a well-known modulator of fetal neuroendocrine activity, and has been proposed as a critical endocrine signal readying the fetus for birth and postnatal life. To investigate the modulatory role of E2 on fetal stress responsiveness and the response of the fetal brain to asphyxic stress, we subjected chronically catheterized fetal sheep to a transient (10 min) brachiocephalic occlusion or sham occlusion. Half of the fetuses received subcutaneous pellets that released E2 (5 days@~250 M-NM-

ORGANISM(S): Ovis aries

SUBMITTER: Charles Wood 

PROVIDER: E-GEOD-52888 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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