Unknown,Transcriptomics,Genomics,Proteomics

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Gene expression of non-typeable Haemophilus influenzae strain R2866 and R2866Δ0112 mutant grown in supplemented brain-heart infusion medium


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Haemophilus influenzae R2866

SUBMITTER: Jeroen Langereis 

PROVIDER: E-GEOD-53290 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Modified lipooligosaccharide structure protects nontypeable Haemophilus influenzae from IgM-mediated complement killing in experimental otitis media.

Langereis Jeroen D JD   Stol Kim K   Schweda Elke K EK   Twelkmeyer Brigitte B   Bootsma Hester J HJ   de Vries Stefan P W SP   Burghout Peter P   Diavatopoulos Dimitri A DA   Hermans Peter W M PW  

mBio 20120703 4


<h4>Unlabelled</h4>Nontypeable Haemophilus influenzae (NTHi) is a Gram-negative, human-restricted pathogen. Although this bacterium typically colonizes the nasopharynx in the absence of clinical symptoms, it is also one of the major pathogens causing otitis media (OM) in children. Complement represents an important aspect of the host defense against NTHi. In general, NTHi is efficiently killed by complement-mediated killing; however, various resistance mechanisms have also evolved. We measured t  ...[more]

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