Gene expression profiles of ovarian cancer cells by inhibiting Hh signaling
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ABSTRACT: Analysis of gene expression levels in response to inhibition of Hh signaling in ovarian cancer cells using a cDNA microarray technique. Results suggest that 208 genes (50.5%) were up-regulated and 204 gene (49.5%) were down-regulated after GANT61 treatment.The focal adhesion and ECM-receptor interaction cross-talk in SKOV3 cells after treatment with GANT61, and the expression change of “focal adhesion” related genes play an important role in the processes of response to GANT61-treatment. SKOV3 cells were treated with GANT61 (20 μM for 60 hr) and control vehicle DMSO, respectively.
ORGANISM(S): Homo sapiens
SUBMITTER: Shiwen Luo
PROVIDER: E-GEOD-53464 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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