Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Sabine Bahn
PROVIDER: E-GEOD-5388 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Molecular psychiatry 20060808 10
Bipolar affective disorder is a severe psychiatric disorder with a strong genetic component but unknown pathophysiology. We used microarray technology to determine the expression of approximately 22,000 mRNA transcripts in post-mortem tissue from two brain regions in patients with bipolar disorder and matched healthy controls. Dorsolateral prefrontal cortex tissue from a cohort of 70 subjects and orbitofrontal cortex tissue from a separate cohort of 30 subjects was investigated. The final analys ...[more]