Unknown,Transcriptomics,Genomics,Proteomics

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A genomic and clinical prognostic index for hepatitis C-related early-stage cirrhosis that predicts clinical deterioration


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens

SUBMITTER: Yujin Hoshida 

PROVIDER: E-GEOD-54102 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications


<h4>Objective</h4>The number of patients with HCV-related cirrhosis is increasing, leading to a rising risk of complications and death. Prognostic stratification in patients with early-stage cirrhosis is still challenging. We aimed to develop and validate a clinically useful prognostic index based on genomic and clinical variables to identify patients at high risk of disease progression.<h4>Design</h4>We developed a prognostic index, comprised of a 186-gene signature validated in our previous ge  ...[more]

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