Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Yujin Hoshida
PROVIDER: E-GEOD-54102 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
King Lindsay Y LY Canasto-Chibuque Claudia C Johnson Kara B KB Yip Shun S Chen Xintong X Kojima Kensuke K Deshmukh Manjeet M Venkatesh Anu A Tan Poh Seng PS Sun Xiaochen X Villanueva Augusto A Sangiovanni Angelo A Nair Venugopalan V Nair Venugopalan V Mahajan Milind M Kobayashi Masahiro M Kumada Hiromitsu H Iavarone Massimo M Colombo Massimo M Fiel Maria Isabel MI Friedman Scott L SL Llovet Josep M JM Chung Raymond T RT Hoshida Yujin Y
Gut 20140820 8
<h4>Objective</h4>The number of patients with HCV-related cirrhosis is increasing, leading to a rising risk of complications and death. Prognostic stratification in patients with early-stage cirrhosis is still challenging. We aimed to develop and validate a clinically useful prognostic index based on genomic and clinical variables to identify patients at high risk of disease progression.<h4>Design</h4>We developed a prognostic index, comprised of a 186-gene signature validated in our previous ge ...[more]