Expression data from peripheral blood mononuclear cells of subjects supplemented with vitamin C
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Guido Leoni
PROVIDER: E-GEOD-54477 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Vitamin C supplementation modulates gene expression in peripheral blood mononuclear cells specifically upon an inflammatory stimulus: a pilot study in healthy subjects.
Canali Raffaella R Natarelli Lucia L Leoni Guido G Azzini Elena E Comitato Raffaella R Sancak Oezgur O Barella Luca L Virgili Fabio F
Genes & nutrition 20140307 3
In order to study the effects of vitamin C supplementation on gene expression and compare its action between physiological and inflammatory conditions, a pilot study was set up utilizing microarray and qPCR technologies. Five healthy volunteers were supplemented with 1 g vitamin C (Redoxon(®)) per day for five consecutive days. Peripheral blood mononuclear cells (PBMNC) were isolated before and just after the last supplementation, and RNA was isolated for the Affymetrix gene 1.0 ST chip analysis ...[more]
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