Expression data from Rat liver 48 hours after treated with different toxic compounds.
Ontology highlight
ABSTRACT:
ORGANISM(S): Rattus norvegicus
SUBMITTER: Jeppe Spicker
PROVIDER: E-GEOD-5509 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Integration of clinical chemistry, expression, and metabolite data leads to better toxicological class separation.
Spicker Jeppe S JS Brunak Søren S Frederiksen Klaus S KS Toft Henrik H
Toxicological sciences : an official journal of the Society of Toxicology 20080104 2
A large number of databases are currently being implemented within toxicology aiming to integrate diverse biological data, such as clinical chemistry, expression, and other types of data. However, for these endeavors to be successful, tools for integration, visualization, and interpretation are needed. This paper presents a method for data integration using a hierarchical model based on either principal component analysis or partial least squares discriminant analysis of clinical chemistry, expr ...[more]
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