Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Whole transcription data for mouse spermatogonial cells


ABSTRACT: Spermatogenesis is a multi-step yet tightly regulated developmental process to produce male gemetes for reproduction. In mouse spermatogenesis, a sub-group of type A spermatogonia (Spga) known as spermatogonial stem cells (SSCs) maintain their population by self-renewal, and differentiate through mitosis and meiosis to form tetraploid (4n) pacchytene spermatocytes (Spcy) and haploid (n) round spermatids (Sptd), which further differentiate into functional sperms. In this study, we selected three representative stages of mouse spermatogenesis, namely Spga, Spcy and Sptd, to study their transcriptomic charteristics using whole genome tiling microarray. Three biological replicates of each selected stage. Spga were isolated from 6-day-old Balb/c mice, Spcy and Sptd from 60-day-old Balb/c mice.

ORGANISM(S): Mus musculus

SUBMITTER: Tin-Lap Lee 

PROVIDER: E-GEOD-55381 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress