Gene expression profile of TRAIL-sensitive and -resistant H460 cells
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ABSTRACT: We generated H460 cells with acquired TRAIL resistance by exposing the parental sentisitve cells to subtoxic concentrations of TRAIL for 6 months. Then we compared the gene expression profile of the sensitive versus the resistant cells. We generated acquired TRAIL-resistant H460 cells from the sentisitve cells by treating subtoxic range of TRAIL for 6 month. And we tried to compare the expressional profile of the genes between two cell types to isolate genes regulating acquired TRAIL-resistance H460 cells were treated with subtoxic concentrations of TRAIL for 6 month. After confirmation of the resistance, the RNA was extracted and the gene expression profile was analyzed.
ORGANISM(S): Homo sapiens
SUBMITTER: Carlo Croce
PROVIDER: E-GEOD-55859 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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