Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Transcriptomics and methylomics of human monocytes


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens

SUBMITTER: Yongmei Liu 

PROVIDER: E-GEOD-56047 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications


Age-related variations in DNA methylation have been reported; however, the functional relevance of these differentially methylated sites (age-dMS) are unclear. Here we report potentially functional age-dMS, defined as age- and cis-gene expression-associated methylation sites (age-eMS), identified by integrating genome-wide CpG methylation and gene expression profiles collected ex vivo from circulating T cells (227 CD4+ samples) and monocytes (1,264 CD14+ samples, age range: 55-94 years). None of  ...[more]

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