Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Dan Sturdevant
PROVIDER: E-GEOD-56168 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Porcella Stephen F SF Carlson John H JH Sturdevant Daniel E DE Sturdevant Gail L GL Kanakabandi Kishore K Virtaneva Kimmo K Wilder Hannah H Whitmire William M WM Song Lihua L Caldwell Harlan D HD
Infection and immunity 20141117 2
Chlamydia trachomatis is an obligate intracellular epitheliotropic bacterial pathogen of humans. Infection of the eye can result in trachoma, the leading cause of preventable blindness in the world. The pathophysiology of blinding trachoma is driven by multiple episodes of reinfection of conjunctival epithelial cells, producing an intense chronic inflammatory response resulting in submucosal tissue remodeling and scarring. Recent reports have shown that infection with trachoma organisms lacking ...[more]