Dataset Information
Transcription profiling of human HeLa CD4+ cells treated with nocodazole and hydroxyurea and transfected with epitope-tagged eTat plasmid sampled at multiple time points
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Winnie Liang
PROVIDER: E-GEOD-571 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Therapeutic targets for HIV-1 infection in the host proteome.
Retrovirology 20050321
<h4>Background</h4>Despite the success of HAART, patients often stop treatment due to the inception of side effects. Furthermore, viral resistance often develops, making one or more of the drugs ineffective. Identification of novel targets for therapy that may not develop resistance is sorely needed. Therefore, to identify cellular proteins that may be up-regulated in HIV infection and play a role in infection, we analyzed the effects of Tat on cellular gene expression during various phases of t ...[more]
