RNA-Seq Identifies Novel Myocardial Gene Expression Signatures of Heart Failure [microarray]
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ABSTRACT: We have utilized the RNA-Seq technology to identify genes with distinct expression patterns between failing and non-failing hearts. In an era of next-generation sequencing studies, our study demonstrates how knowledge gained from a small set of samples with accurately measured gene expressions using RNA-Seq can be leveraged as a complementary strategy to discern the genetics of complex disorders. Identify the signature genes based on RNA-seq come from six Heart Failure and healthy individuals. Validation is based on Affymetrix microarray of a total of 313 individuals with/without Heart Failure.
ORGANISM(S): Homo sapiens
SUBMITTER: Michael Morley
PROVIDER: E-GEOD-57338 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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