Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Sherif Elela
PROVIDER: E-GEOD-57448 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Gagnon Jules J Lavoie Mathieu M Catala Mathieu M Malenfant Francis F Elela Sherif Abou SA
PLoS genetics 20150213 2
Detection and validation of the RNA degradation signals controlling transcriptome stability are essential steps for understanding how cells regulate gene expression. Here we present complete genomic and biochemical annotations of the signals required for RNA degradation by the dsRNA specific ribonuclease III (Rnt1p) and examine its impact on transcriptome expression. Rnt1p cleavage signals are randomly distributed in the yeast genome, and encompass a wide variety of sequences, indicating that tr ...[more]