Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Expression profiles in HMGN1-overexpressed neural precursor cells


ABSTRACT: Neural precursor cells (NPCs) are multipotent cells that can generate neurons, astrocytes, and oligodendrocytes in the mammalian central nervous system. Although high mobility group nucleosomal binding domain 1 (HMGN1) was highly expressed in NPCs, its functions in neural development are not fully understood. We performed microarray analysis to examine changes in gene expression between control and HMGN1-overexpressed NPCs. NPCs derived from E11.5 mouse forebrains were infected with control or HMGN1 retrovirus in the presence of fibroblast growth factor 2 (FGF2) and epidermal growth factor (EGF). Three days after infection, the virus-infected NPCs were dissociated and seeded on poly-D-lysine -coated dishes, and subsequently the cells were cultured for 1 day without FGF2 and EGF.

ORGANISM(S): Mus musculus

SUBMITTER: Motoshi Nagao 

PROVIDER: E-GEOD-57534 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2014-01-16 | E-GEOD-54086 | biostudies-arrayexpress
2014-09-01 | GSE57534 | GEO
2015-04-30 | E-GEOD-60060 | biostudies-arrayexpress
2013-10-01 | E-MEXP-3883 | biostudies-arrayexpress
2014-11-21 | E-GEOD-55541 | biostudies-arrayexpress
2013-08-13 | E-GEOD-48336 | biostudies-arrayexpress
2016-03-14 | E-GEOD-63738 | biostudies-arrayexpress
2014-04-01 | E-GEOD-40102 | biostudies-arrayexpress
2016-03-01 | E-GEOD-74378 | biostudies-arrayexpress
2023-08-29 | E-MTAB-13161 | biostudies-arrayexpress