Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Expression data measured by Nanostring and microarray of monocyte-derived dendritic cells from healthy individuals stimulated with LPS, influenza, or IFN-beta, or left unstimulated


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens

SUBMITTER: Nir Hacohen 

PROVIDER: E-GEOD-57542 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

altmetric image

Publications


Little is known about how human genetic variation affects the responses to environmental stimuli in the context of complex diseases. Experimental and computational approaches were applied to determine the effects of genetic variation on the induction of pathogen-responsive genes in human dendritic cells. We identified 121 common genetic variants associated in cis with variation in expression responses to Escherichia coli lipopolysaccharide, influenza, or interferon-β (IFN-β). We localized and va  ...[more]

Similar Datasets

2014-03-01 | E-GEOD-53165 | biostudies-arrayexpress
2014-03-01 | E-GEOD-53166 | biostudies-arrayexpress
2014-08-28 | E-GEOD-60341 | biostudies-arrayexpress
2015-04-28 | E-GEOD-68306 | biostudies-arrayexpress
2013-04-19 | E-GEOD-41970 | biostudies-arrayexpress
2013-12-30 | E-GEOD-41372 | biostudies-arrayexpress
2016-02-01 | E-GEOD-55770 | biostudies-arrayexpress
2012-07-25 | E-GEOD-39644 | biostudies-arrayexpress
2014-08-22 | E-GEOD-54099 | biostudies-arrayexpress
2014-08-22 | E-GEOD-54100 | biostudies-arrayexpress