Effect of CHADL knockdown in ATDC cells
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ABSTRACT: The human genome contains several homologous Small Leucine-Rich Protein (SLRP)-encoding genes, many of which orchestrate collagen fibril assembly. All SLRP gene products have not been identified or characterized. In this report, we describe a novel class IV SLRP - Chondroadherin-like (CHADL). Microarray analysis of CHADL knockdown in ATDC5 cells suggests collagen receptor-related changes, a pro-proliferative and pro-differentiation profile. Two samples in duplicates are analyzed. The two control samples are transfected with scrambled negative control shRNA.The two knockdown samples are transfected with shRNA specific for CHADL.
ORGANISM(S): Mus musculus
SUBMITTER: James Ho
PROVIDER: E-GEOD-57740 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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