Molecular effects of capsaicin on human gingival epithelial cells
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ABSTRACT: In order to explain the molecular mechanisms of capsaicin-induced proliferation of gingival epithelial cells (GECs), a microarray analysis was performed. Several cell proliferation related genes were significantly up-regulated. These data suggest that TRPV1 signaling in GEC may induce transcriptional upregulation of growth factors, which results in an increased proliferation rate. Simian virus 40 (SV40) T-antigen-immortalized human gingival epithelial cell line, epi4, were stimulated with 1 M-NM-
ORGANISM(S): Homo sapiens
SUBMITTER: Naoki Takahashi
PROVIDER: E-GEOD-57759 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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