Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Minhyung Kim
PROVIDER: E-GEOD-59042 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
The international journal of biochemistry & cell biology 20150507
Mechanisms associated with the progression of non-alcoholic fatty liver disease (NAFLD) remain unclear. We attempted to identify the pattern of altered gene expression at different time points in a high fat diet (HFD)-induced NAFLD mouse model. The early up-regulated genes are mainly involved in the innate immune responses, while the late up-regulated genes represent the inflammation processes. Although recent studies have shown that microRNAs play important roles in hepatic metabolic functions, ...[more]