Transcription profiling of human skin biopsies from atopic eczema and healthy controls
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Mikael Benson
PROVIDER: E-GEOD-6012 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Increased expression of aquaporin 3 in atopic eczema.
Olsson M M Broberg A A Jernås M M Carlsson L L Rudemo M M Suurküla M M Svensson P-A PA Benson M M
Allergy 20060901 9
<h4>Background</h4>Dry skin in atopic eczema depends on increased water loss. The mechanisms behind this are poorly understood. The aim of this work was to identify genes that may contribute to water loss in eczema.<h4>Methods</h4>Affymetrix DNA microarrays U133A were used to analyse gene expression in skin biopsies from 10 patients with atopic eczema and 10 healthy controls.<h4>Results</h4>DNA microarray analysis showed up-regulation of 262 genes and down-regulation of 129 genes in atopic eczem ...[more]
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