Unknown,Transcriptomics,Genomics,Proteomics

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RNA profiling in Drosophila virilis and Drosophila yakuba

ABSTRACT: Gene annoation and determination of gene expression levels in Drosophila virilis and Drosophila yakuba by deep sequencing. Total RNA-seq data from heads of 2-5 day old mated D virilis and D yakuba females, 1 sample from each species.

ORGANISM(S): Drosophila yakuba

SUBMITTER: Eric Lai 

PROVIDER: E-GEOD-61222 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Genome-wide analysis of drosophila circular RNAs reveals their structural and sequence properties and age-dependent neural accumulation.

Westholm Jakub O JO   Miura Pedro P   Olson Sara S   Shenker Sol S   Joseph Brian B   Sanfilippo Piero P   Celniker Susan E SE   Graveley Brenton R BR   Lai Eric C EC  

Cell reports 20141126 5

Circularization was recently recognized to broadly expand transcriptome complexity. Here, we exploit massive Drosophila total RNA-sequencing data, >5 billion paired-end reads from >100 libraries covering diverse developmental stages, tissues, and cultured cells, to rigorously annotate >2,500 fruit fly circular RNAs. These mostly derive from back-splicing of protein-coding genes and lack poly(A) tails, and the circularization of hundreds of genes is conserved across multiple Drosophila species. W  ...[more]

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