Comparative microRNA profiling of sporadic and BRCA1 associated basal-like breast cancers
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ABSTRACT: Analysis of miRNA expression in grade 3 luminal, sporadic and BRCA1 associated basal-like breast cancers 44 primary grade III breast cancer (11 BRCA1 basal, 16 sporadic basal, 17 luminal) and 13 normal breast FFPE (formalin fixed, paraffin embedded) specimens, plus 7 controls and 5 cell lines were analysed. The aim of the study was to derive grade-specific miRNA signatures for sporadic and BRCA1 basal-like breast cancers, and to ascertain an immunohistochemical profile regulated by BRCA1 specific miRNAs for potential diagnostic uses.
ORGANISM(S): Homo sapiens
SUBMITTER: Max Yan
PROVIDER: E-GEOD-61438 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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