Unknown,Transcriptomics,Genomics,Proteomics

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Gene expression profiling of small bowel adenocarcinoma


ABSTRACT: The whole genome DASL HT assay was used in combination with the HumanHT-12 v4 BeadChip for screening normal and tumour tissue in a retrospective 28 sample cohort of small bowel adenocarcinoma patients. Non-normalized and average normalized (background subtracted) data Comparing differences in gene expression in a matched normal tumour cohort of 28 small bowel adenocarcinoma patients.

ORGANISM(S): Homo sapiens

SUBMITTER: Muhammad Alvi 

PROVIDER: E-GEOD-61465 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Small bowel accounts for only 0.5% of cancer cases in the US but incidence rates have been rising at 2.4% per year over the past decade. One-third of these are adenocarcinomas but little is known about their molecular pathology and no molecular markers are available for clinical use. Using a retrospective 28 patient matched normal-tumor cohort, next-generation sequencing, gene expression arrays and CpG methylation arrays were used for molecular profiling. Next-generation sequencing identified no  ...[more]

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