Astrocyte elevated gene-1 (AEG-1) and c-Myc cooperate to promote hepatocarcinogenesis

ABSTRACT: Double transgenic mice with hepatocyte-specific expression of AEG-1 and c-Myc show aggressive HCC compared to single transgenics. Gene expression was analyzed to understand the molecular mechanism by which AEG-1 and c-Myc cooperate to promote hepatocarcinogenesis. Livers were collected from naïve adult mice (3 mice/group). Total RNA was extrancted and subjected to RNA-Seq.

ORGANISM(S): Mus musculus

SUBMITTER: Hung-I Chen 

PROVIDER: E-GEOD-61875 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress