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Combination of epigenetic, differentiation and DNA damaging agents induce tumor cell death and stem cell depletion in breast cancer

ABSTRACT: Gene expression profiles were performed on MDA-MB-231 TNBC cell line treated with entinostast, all-trans retinoic acid (ATRA), and doxorubicin as single, double, and triple combinations using Illumina. Treatment signatures were made from each drug treatment and integrated to find a comprehensive view of changes associated with the epigenetic, differentiation and chemotherapy combination

ORGANISM(S): Homo sapiens

SUBMITTER: Saraswati Sukumar

PROVIDER: E-GEOD-63351 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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