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Differences of miRNA expression profiling between GIST and leiomyoma tissue samples acquired by Tunneling Bloc Biopsy

ABSTRACT: miRNA expression profiling between GIST and leiomyoma specimens taken by Tunneling Bloc Biopsy Nine GIST patients and seven gastric leiomyoma patients underwent endoscopic biopsy called Tunnel Block Biopsy. MiRNAs were extracted from the tissues, then.

ORGANISM(S): Homo sapiens

SUBMITTER: Satoshi Kondo

PROVIDER: E-GEOD-63453 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Differences in miRNA expression profiles between GIST and leiomyoma in human samples acquired by submucosal tunneling biopsy.

Fujita Koji K Kobara Hideki H Mori Hirohito H Fujihara Shintaro S Chiyo Taiga T Matsunaga Tae T Nishiyama Noriko N Ayaki Maki M Yachida Tatsuo T Morishita Asahiro A Fujiwara Masao M Okano Keiichi K Suzuki Yasuyuki Y Iwama Hisakazu H Masaki Tsutomu T

Endoscopy international open 20150923 6

<h4>Background and study aims</h4>Small gastrointestinal stromal tumors (GISTs) rarely have malignant potential with poor prognosis. Using conventional imaging to differentiate between small GISTs and leiomyoma, which often have similar characteristics, is difficult but essential in daily practice. Although some studies have reported on the utility of serum c-kit as a biomarker for non-small GIST and specific miRNA, clinical aspects of such testing are controversial. The aim of this study was to ...[more]

PMID: 26716134

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