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Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of cutaneous lesions caused by Leishmania braziliensis and normal skin.

ABSTRACT: This study was carried out to evaluate the changes that occur in the skin after the development of cutaneous leishmaniasis, aiming at a comprehensive understanding of immune pathways and biological functions activated in lesions caused by L. braziliensis. This analysis was conducted on 8 skin ulcers from patients infected with L. braziliensis. The patients selected for the gene expression analysis had recent L. braziliensis infection that had not yet been treated. 8 controls samples are skin biopsies from healthy donors (non-infected).

ORGANISM(S): Homo sapiens

SUBMITTER: Pablo Oliveira

PROVIDER: E-GEOD-63931 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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CD8 T cells induce perforin-dependent pathology in Leishmania braziliensis infection

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