Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Steve Horvath
PROVIDER: E-GEOD-64509 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Aging 20150501 5
Studies that elucidate why some human tissues age faster than others may shed light on how we age, and ultimately suggest what interventions may be possible. Here we utilize a recent biomarker of aging (referred to as epigenetic clock) to assess the epigenetic ages of up to 30 anatomic sites from supercentenarians (subjects who reached an age of 110 or older) and younger subjects. Using three novel and three published human DNA methylation data sets, we demonstrate that the cerebellum ages more ...[more]