Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Expression data from Incidental vs. Surgical BPH samples


ABSTRACT: used to identify differences between tissues from patients undergoing surgery for BPH with unresolved symptoms compared to incidental BPH from patients with prostate cancer cohorts are based on surgical distinction

ORGANISM(S): Homo sapiens

SUBMITTER: douglas strand 

PROVIDER: E-GEOD-65343 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Surgical intervention for symptomatic benign prostatic hyperplasia is correlated with expression of the AP-1 transcription factor network.

Lin-Tsai Opal O   Clark Peter E PE   Miller Nicole L NL   Fowke Jay H JH   Hameed Omar O   Hayward Simon W SW   Strand Douglas W DW  

The Prostate 20140205 6


<h4>Background</h4>Approximately one-third of patients fail medical treatment for benign prostatic hyperplasia and associated lower urinary tract symptoms (BPH/LUTS) requiring surgical intervention. Our purpose was to establish a molecular characterization for patients undergoing surgical intervention for LUTS to address therapeutic deficiencies.<h4>Methods</h4>Clinical, molecular, and histopathological profiles were analyzed in 26 patients undergoing surgery for severe LUTS. Incidental transiti  ...[more]

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