Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Vasanth Vedantham
PROVIDER: E-GEOD-65658 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Vedantham Vasanth V Galang Giselle G Evangelista Melissa M Deo Rahul C RC Srivastava Deepak D
Circulation research 20150126 5
<h4>Rationale</h4>Treatment of sinus node disease with regenerative or cell-based therapies will require a detailed understanding of gene regulatory networks in cardiac pacemaker cells (PCs).<h4>Objective</h4>To characterize the transcriptome of PCs using RNA sequencing and to identify transcriptional networks responsible for PC gene expression.<h4>Methods and results</h4>We used laser capture microdissection on a sinus node reporter mouse line to isolate RNA from PCs for RNA sequencing. Differe ...[more]