Genome-wide blood transcriptional profiling in critically ill patients - MARS consortium
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Brendon Scicluna
PROVIDER: E-GEOD-65682 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admission.
Scicluna Brendon P BP Klein Klouwenberg Peter M C PM van Vught Lonneke A LA Wiewel Maryse A MA Ong David S Y DS Zwinderman Aeilko H AH Franitza Marek M Toliat Mohammad R MR Nürnberg Peter P Hoogendijk Arie J AJ Horn Janneke J Cremer Olaf L OL Schultz Marcus J MJ Bonten Marc J MJ van der Poll Tom T
American journal of respiratory and critical care medicine 20151001 7
<h4>Rationale</h4>Community-acquired pneumonia (CAP) accounts for a major proportion of intensive care unit (ICU) admissions for respiratory failure and sepsis. Diagnostic uncertainty complicates case management, which may delay appropriate cause-specific treatment.<h4>Objectives</h4>To characterize the blood genomic response in patients with suspected CAP and identify a candidate biomarker for the rapid diagnosis of CAP on ICU admission.<h4>Methods</h4>The study comprised two cohorts of consecu ...[more]
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2013-04-03 | E-MEXP-3850 | biostudies-arrayexpress