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Effects of the histone demethylase LSD1/KDM1A on the gene expression program of murine hematopoietic progenitor cells.

ABSTRACT: We established transgenic mice overexpressing the histone demethyase LSD1/KDM1A under the control of Sca-1 promoter and investigated the global changes in gene expression in hematopoietic progenitor cells using a microarray- based approach. We isolated mRNA from Sca-1-positive hematopoietic progenitor cells from two transgenic mice, Line 6 and Line 3, and subjected them to gene expression analysis using an Affimetrix GeneChip Array.

ORGANISM(S): Mus musculus

SUBMITTER: Yusuke Furukawa

PROVIDER: E-GEOD-66074 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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