Unknown,Transcriptomics,Genomics,Proteomics

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Comparison of normal and heat shock trophozoites


ABSTRACT: We examined the stress response in Entamoeba histolytica trophozoites by comparing untreated log-phase HM-1:IMSS trophozoites to those subjected to heat shock at 42C for 1 hour. Keywords: stress reponse We compared two arrays from normal trophozoites to two arrays from trophozoites subjected to heat shock.

ORGANISM(S): Entamoeba histolytica

SUBMITTER: Gretchen Ehrenkaufer 

PROVIDER: E-GEOD-6650 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Identification of putative transcriptional regulatory networks in Entamoeba histolytica using Bayesian inference.

Hackney Jason A JA   Ehrenkaufer Gretchen M GM   Singh Upinder U  

Nucleic acids research 20070313 7


Few transcriptional regulatory networks have been described in non-model organisms. In Entamoeba histolytica seminal aspects of pathogenesis are transcriptionally controlled, however, little is known about transcriptional regulatory networks that effect gene expression in this parasite. We used expression data from two microarray experiments, cis-regulatory motif elucidation, and a naïve Bayesian classifier to identify genome-wide transcriptional regulatory patterns in E. histolytica. Our algori  ...[more]

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