Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Transcriptome analyses of skeletal muscle in αB-crystallin/HspB2 knockout and wild-type mice on a normal or high fat diet


ABSTRACT: We profiled the skeletal muscle transcriptome between wild type and αB-crystallin/HspB2 knock mice exposed to normal chow and high fat diets to examine the role of αB-crystallin/HspB2 in diet induced obesity. Combined with metabolic profiling of the mice, these data reveal that αB-crystallin/HspB2 is involved in the genesis of insulin resistance on a high fat diet, and we provide extensive RNA profiling to illuminate potential mechanistic insights into the muscle-specific role of αB-crystallin/HspB2. Hind limb muscle mRNA profiles of wild type and αB-crystallin/HspB2 knock mice exposed to either normal chow or high fat diets using RNAseq analysis

ORGANISM(S): Mus musculus

SUBMITTER: Daniel Toft 

PROVIDER: E-GEOD-66557 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2015-09-01 | GSE66557 | GEO
2016-01-07 | E-GEOD-64824 | biostudies-arrayexpress
2015-08-28 | E-GEOD-68360 | biostudies-arrayexpress
2014-09-26 | GSE60151 | GEO
2016-06-01 | E-GEOD-70016 | biostudies-arrayexpress
2024-01-08 | PXD040991 | Pride
2024-10-30 | PXD054323 | Pride
2023-02-21 | GSE225548 | GEO
2023-03-01 | GSE220302 | GEO
2016-02-08 | E-GEOD-67207 | biostudies-arrayexpress