Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Qi Ma
PROVIDER: E-GEOD-66709 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Neuron 20150416 3
One of the exceptional properties of the brain is its ability to acquire new knowledge through learning and to store that information through memory. The epigenetic mechanisms linking changes in neuronal transcriptional programs to behavioral plasticity remain largely unknown. Here, we identify the epigenetic signature of the neuronal enhancers required for transcriptional regulation of synaptic plasticity genes during memory formation, linking this to Reelin signaling. The binding of Reelin to ...[more]