Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Pedro Jares
PROVIDER: E-GEOD-6728 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Blood 20070301 12
Mantle-cell lymphoma (MCL) is genetically characterized by the translocation t(11;14)(q13;q32) and a high number of secondary chromosomal abnormalities. To identify genes inactivated in this lymphoma, we examined 5 MCL cell lines following a strategy previously described in tumors with microsatellite instability that is based on the combined inhibition of the nonsense-mediated mRNA decay pathway and gene-expression profiling. This approach, together with the design of a conservative algorithm fo ...[more]