Unknown,Transcriptomics,Genomics,Proteomics

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Cbl family proteins are required to maintain the proteome homeostasis in mammary epithelial cells


ABSTRACT: EGFR degradation is delayed in Cbl, Cbl-b double-deficient MCF10A but EGF stimulation does not enhance their growth. We performed a transcriptome analysis to gain insights into biological consequences of Cbl, Cbl-b loss in mammary epithelial cells. We compared the transcriptome of MCF10A cells expressing shRNA against Cbl and Cbl-b with control shRNA-expressing cells using Affymetrix U133 Plus 2.0. Each sample was prepared in duplicates. Data were analyzed by GSEA.

ORGANISM(S): Homo sapiens

SUBMITTER: Mayumi Naramura 

PROVIDER: E-GEOD-67301 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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