Identification of novel, highly expressed retroviral microRNAs in cells infected by bovine foamy virus
Ontology highlight
ABSTRACT:
ORGANISM(S): Bos taurus
SUBMITTER: Adam Whisnant
PROVIDER: E-GEOD-67620 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Identification of novel, highly expressed retroviral microRNAs in cells infected by bovine foamy virus.
Whisnant Adam W AW Kehl Timo T Bao Qiuying Q Materniak Magdalena M Kuzmak Jacek J Löchelt Martin M Cullen Bryan R BR
Journal of virology 20140212 9
<h4>Unlabelled</h4>While numerous viral microRNAs (miRNAs) expressed by DNA viruses, especially herpesvirus family members, have been reported, there have been very few reports of miRNAs derived from RNA viruses. Here we describe three miRNAs expressed by bovine foamy virus (BFV), a member of the spumavirus subfamily of retroviruses, in both BFV-infected cultured cells and BFV-infected cattle. All three viral miRNAs are initially expressed in the form of an ∼ 122-nucleotide (nt) pri-miRNA, encod ...[more]
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