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MiRNA expression profile of 14 mouse tissues

ABSTRACT: We sequenced 14 mouse tissues' small RNA samples from C57BL/6J mouse and aligned the sequenced reads to miRBase_v16 to profile miRNA expression levels in these 14 tissues. We collect several tissue samples from 10 C57BL/6J mouse. Use high-throughout sequence technology to profile miRNA expression level in each tissue.

ORGANISM(S): Mus musculus

SUBMITTER: Zhen Zhou 

PROVIDER: E-GEOD-67885 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

MicroRNA-196a/b Mitigate Renal Fibrosis by Targeting TGF-β Receptor 2.

Meng Jiao J   Li Limin L   Zhao Yue Y   Zhou Zhen Z   Zhang Mingchao M   Li Donghai D   Zhang Chen-Yu CY   Zen Ke K   Liu Zhihong Z  

Journal of the American Society of Nephrology : JASN 20160303 10

Organ-specific microRNAs have essential roles in maintaining normal organ function. However, the microRNA profile of the kidney and the role of microRNAs in modulating renal function remain undefined. We performed an unbiased assessment of the genome-wide microRNA expression profile in 14 mouse organs using Solexa deep sequencing and found that microRNA-196a (miR-196a) and miR-196b are selectively expressed in kidney, with 74.37% of mouse total miR-196a and 73.19% of mouse total miR-196b distrib  ...[more]

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