Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Brian Black
PROVIDER: E-GEOD-68147 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Barnes Ralston M RM Harris Ian S IS Jaehnig Eric J EJ Sauls Kimberly K Sinha Tanvi T Rojas Anabel A Schachterle William W McCulley David J DJ Norris Russell A RA Black Brian L BL
Development (Cambridge, England) 20160125 5
Congenital heart defects are the most common birth defects in humans, and those that affect the proper alignment of the outflow tracts and septation of the ventricles are a highly significant cause of morbidity and mortality in infants. A late differentiating population of cardiac progenitors, referred to as the anterior second heart field (AHF), gives rise to the outflow tract and the majority of the right ventricle and provides an embryological context for understanding cardiac outflow tract a ...[more]