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Sphere-Derived Multipotent Progenitor Cells Obtained From Human Oral Mucosa Are Enriched in Neural Crest Cells.

ABSTRACT: The purpose of this study was to isolate NCSCs from oral mucosa using the neurosphere technique. Total RNA from human oral mucosa stromal cells and sphere-formig oral mucosa stromal cells was collected and compared at their gene expression level. Samples from 3 patients were analysed.

ORGANISM(S): Homo sapiens

SUBMITTER: Shigehiro Abe

PROVIDER: E-GEOD-68636 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Sphere-Derived Multipotent Progenitor Cells Obtained From Human Oral Mucosa Are Enriched in Neural Crest Cells.

Abe Shigehiro S Yamaguchi Satoshi S Sato Yutaka Y Harada Kiyoshi K

Stem cells translational medicine 20151118 1

<h4>Unlabelled</h4>: Although isolation of oral mucosal stromal stem cells has been previously reported, complex isolation methods are not suitable for clinical application. The neurosphere culture technique is a convenient method for the isolation of neural stem cells and neural crest stem cells (NCSCs); neurosphere generation is a phenotype of NCSCs. However, the molecular details underlying the isolation and characterization of human oral mucosa stromal cells (OMSCs) by neurosphere culture ar ...[more]

PMID: 26582909

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