Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Peter Lee
PROVIDER: E-GEOD-6887 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
PLoS medicine 20070501 5
<h4>Background</h4>Dysfunction of the immune system has been documented in many types of cancers. The precise nature and molecular basis of immune dysfunction in the cancer state are not well defined.<h4>Methods and findings</h4>To gain insights into the molecular mechanisms of immune dysfunction in cancer, gene expression profiles of pure sorted peripheral blood lymphocytes from 12 patients with melanoma were compared to 12 healthy controls. Of 25 significantly altered genes in T cells and B ce ...[more]