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MiRNA Profiles in lung cancer patients and controls with other non-cancer lung diseases

ABSTRACT: This project analyzes plasma profiles of patients suffering from lung cancer and controls with other non-cancer lung diseases Analysis of plasma obtained from 26 patients collected at up to 8 time points and from 12 controls

ORGANISM(S): Homo sapiens

SUBMITTER: Christina Backes

PROVIDER: E-GEOD-68951 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Longitudinal study on circulating miRNAs in patients after lung cancer resection.

Leidinger Petra P Galata Valentina V Backes Christina C Stähler Cord C Rheinheimer Stefanie S Huwer Hanno H Meese Eckart E Keller Andreas A

Oncotarget 20150601 18

There is an urgent need of comprehensive longitudinal analyses of circulating miRNA patterns to identify dynamic changes of miRNAs in cancer patients after surgery. Here we provide longitudinal analysis of 1,205 miRNAs in plasma samples of 26 patients after lung cancer resection at 8 time points over a period of 18 months and compare them to 12 control patients. First, we report longitudinal changes with respect to the number of detected miRNAs over time and identified a significantly increased ...[more]

PMID: 26078336

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