Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Histone genes transcription regulators binding in human cancer (U2OS) and normal (hTERT-RPE1) cells


ABSTRACT: The regulation of replication-dependent histone genes by CASP8AP2 and NPAT is likely direct, based on ChIP-seq. CASP8AP2 and NPAT ChIP-Seq peaks were enriched near transcription start sites (TSSs) of replication-dependent, but not replication-independent histone genes on chromosomes 1, 6 and 12 in both cell lines. HINFP ChIP-Seq peaks were enriched near transcription start sites (TSSs) of replication-dependent histone genes H4 and H2B and replication-independent histone genes H1FX and H1F0 in both cell lines. Another histone gene regulator, E2F1 also bound to TSSs of many histone genes mainly replication-independent. Examination of histone genes transcroption regulators binding by ChIP-seq in normal and cancer cell lines

ORGANISM(S): Homo sapiens

SUBMITTER: Maria Sokolova 

PROVIDER: E-GEOD-69147 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2016-09-01 | GSE69147 | GEO
2015-12-14 | E-GEOD-68952 | biostudies-arrayexpress
2015-06-23 | E-GEOD-62151 | biostudies-arrayexpress
2010-10-18 | E-GEOD-24538 | biostudies-arrayexpress
| phs001433 | dbGaP
2016-10-01 | GSE83506 | GEO
2020-03-24 | PXD014452 | Pride
2015-12-14 | GSE68952 | GEO
2012-04-04 | E-GEOD-36185 | biostudies-arrayexpress
2021-11-01 | GSE109081 | GEO