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Nitrosative stress response in uropathogenic Escherichia coli (UPEC)

ABSTRACT: A strain of UPEC CFT073 lacking the three known NO detoxifiaction mechanisms, Hmp, FlRd and Nrf is used to study the global effect of NO on the pathogen Cultures were anaerobically grown in triplicates under two conditions: Without nitrosative stress or with nitrosative stress, induced by anaerobic growth on nitrate. RNA was extracted from the samples and following rRNA depletion, samples were analyzed by RNA-seq for genome wide transcriptional differences.

ORGANISM(S): Escherichia coli CFT073

SUBMITTER: Stephen Spiro

PROVIDER: E-GEOD-69830 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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